Version 5.4
Bos taurus Gene: AKNA
Summary
InnateDB Gene IDBG-638591.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKNA
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017306
Encoded Proteins
IDBP-690696
AT-hook transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 21606955
[Homo sapiens] AKNA targeted deletion results in susceptibility to pathogen-induced systemic inflammation and causes sudden neonatal death. (Demonstrated in murine model)
PMID 21606955
[Mus musculus] Akna targeted deletion results in susceptibility to pathogen-induced systemic inflammation and causes sudden neonatal death.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106948:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:105223466-105308444
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023012 ENSBTAP00000023012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000106948
View Gene Order
ENSMUSG00000039158
View Gene Order
Cross-References
SwissProt
TrEMBL E1BDC4
UniProt Splice Variant
Entrez Gene 539274
UniGene Bt.105201
RefSeq
HUGO HGNC:24108
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02024582 DAAA02024583 DAAA02024584
GenPept
RNA Seq Atlas 539274

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca