InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: TNC

Summary

InnateDB Gene

IDBG-638654.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNC

Gene Name

tenascin precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000575

Encoded Proteins

IDBP-690813

tenascin C

IDBP-690814

tenascin C

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000041982:
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:105965498-106067887

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000000752	ENSBTAP00000000752
ENSBTAT00000000753	ENSBTAP00000000753

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0045545	syndecan binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0007528	neuromuscular junction development
GO:0008284	positive regulation of cell proliferation
GO:0009611	response to wounding
GO:0010628	positive regulation of gene expression
GO:0014012	peripheral nervous system axon regeneration
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development
GO:0060740	prostate gland epithelium morphogenesis

Cellular Component

GO:0005576	extracellular region
GO:0005604	basement membrane
GO:0005614	interstitial matrix
GO:0005615	extracellular space
GO:0016020	membrane
GO:0031012	extracellular matrix