Bos taurus Gene: PPP2R3A | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-638716.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | PPP2R3A | ||||||||||||
Gene Name | serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha | ||||||||||||
Synonyms | PPP2R3A | ||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000023416 | ||||||||||||
Encoded Proteins |
protein phosphatase 2, regulatory subunit B'', alpha
protein phosphatase 2, regulatory subunit B'', alpha
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073711:
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010] This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B\'/PR61, and B\'\'/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B\'\' family. The B\'\' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B\'\'. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 1:134223427-134394973 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH |
EGFR1 pathway
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REACTOME | |||||||||||||
KEGG |
mRNA surveillance pathway pathway
mRNA surveillance pathway pathway
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INOH |
Insulin receptor signaling pathway
GPCR Dopamine D1like receptor signaling pathway pathway
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PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | A6QNV9 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 787607 | ||||||||||||
UniGene | Bt.104689 Bt.66280 | ||||||||||||
RefSeq | XM_005195983 XM_005200222 XM_005201922 XM_005201921 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC149028 DAAA02003010 DAAA02003011 DAAA02003012 | ||||||||||||
GenPept | AAI49029 | ||||||||||||
RNA Seq Atlas | 100851082 787607 | ||||||||||||