Bos taurus Gene: BT.62809
Summary
InnateDB Gene IDBG-638766.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.62809
Gene Name Protein Wnt
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012914
Encoded Proteins
Protein Wnt
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075290:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%%, 86%% and 71%% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 26:21240570-21244552
Strand Forward strand
Band
Transcripts
ENSBTAT00000017163 ENSBTAP00000017163
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005109 frizzled binding
Biological Process
GO:0007275 multicellular organismal development
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0045165 cell fate commitment
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
disassembly of the destruction complex and recruitment of AXIN to the membrane pathway
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
Signal Transduction pathway
WNT ligand biogenesis and trafficking pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
GPCR ligand binding pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Class B/2 (Secretin family receptors) pathway
Disease pathway
Disease pathway
Signaling by Wnt pathway
WNT ligand biogenesis and trafficking pathway
Signaling by WNT in cancer pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
disassembly of the destruction complex and recruitment of AXIN to the membrane pathway
TCF dependent signaling in response to WNT pathway
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
Signal Transduction pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
KEGG
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Melanogenesis pathway
Pathways in cancer pathway
Basal cell carcinoma pathway
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Melanogenesis pathway
Pathways in cancer pathway
Basal cell carcinoma pathway
INOH
GPCR signaling pathway
Wnt signaling pathway pathway
GPCR signaling pathway
Wnt signaling pathway pathway
PID BIOCARTA
Wnt lrp6 signalling [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL F1MHG3
UniProt Splice Variant
Entrez Gene 538720
UniGene Bt.62809
RefSeq XM_002698491 XM_582222
HUGO HGNC:12789
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058970
GenPept
RNA Seq Atlas 538720