InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: OFD1

Summary

InnateDB Gene

IDBG-638987.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OFD1

Gene Name

oral-facial-digital syndrome 1 protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004461

Encoded Proteins

IDBP-691109

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000046651:
This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:136925770-136987149

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000005850

ENSBTAP00000005850

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.