InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ARHGDIB

Summary

InnateDB Gene

IDBG-639268.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARHGDIB

Gene Name

Rho GDP-dissociation inhibitor 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006039

Encoded Proteins

IDBP-691408

Rho GDP-dissociation inhibitor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111348:
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:95376923-95395815

Strand

Forward strand

Band

Transcripts

ENSBTAT00000007933

ENSBTAP00000007933

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.