InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.64714

Summary

InnateDB Gene

IDBG-639630.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.64714

Gene Name

collagen alpha-1(III) chain precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000021466

Encoded Proteins

IDBP-691838

collagen alpha-1(III) chain

IDBP-691841

collagen alpha-1(III) chain

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168542:
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:7318227-7356937

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000028617	ENSBTAP00000028617
ENSBTAT00000038678	ENSBTAP00000038490

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0005515	protein binding
GO:0046332	SMAD binding
GO:0048407	platelet-derived growth factor binding

Biological Process

GO:0001568	blood vessel development
GO:0007160	cell-matrix adhesion
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007229	integrin-mediated signaling pathway
GO:0007507	heart development
GO:0009314	response to radiation
GO:0018149	peptide cross-linking
GO:0021987	cerebral cortex development
GO:0030199	collagen fibril organization
GO:0034097	response to cytokine
GO:0035025	positive regulation of Rho protein signal transduction
GO:0042060	wound healing
GO:0043206	extracellular fibril organization
GO:0043588	skin development
GO:0048565	digestive tract development
GO:0050777	negative regulation of immune response
GO:0071230	cellular response to amino acid stimulus
GO:2001223	negative regulation of neuron migration