Bos taurus Gene: COPS6
Summary
InnateDB Gene IDBG-640726.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPS6
Gene Name COP9 signalosome complex subunit 6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002871
Encoded Proteins
COP9 signalosome complex subunit 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168090:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:36893605-36896370
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003725 ENSBTAP00000003725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 258 interaction(s) predicted by orthology.
Predicted by orthology
Total 258 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010388 cullin deneddylation
Cellular Component
GO:0005634 nucleus
GO:0008180 COP9 signalosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL F1MG10
UniProt Splice Variant
Entrez Gene 512756
UniGene
RefSeq NM_001101963
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058286
GenPept
RNA Seq Atlas 512756
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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