Version 5.4
| Bos taurus Gene: RSPO4 | |||
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| Summary | |||
| InnateDB Gene | IDBG-641430.3 | ||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
| Gene Symbol | RSPO4 | ||
| Gene Name | Uncharacterized protein | ||
| Synonyms | RSPO4-like | ||
| Species | Bos taurus | ||
| Ensembl Gene | ENSBTAG00000021885 | ||
| Encoded Proteins |
R-spondin 4
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| Protein Structure | |||
| Useful resources | Stemformatics EHFPI ImmGen | ||
| Entrez Gene | |||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101282:
This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009] |
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| Gene Information | |||
| Type | Protein coding | ||
| Genomic Location | Chromosome 13:60684667-60691970 | ||
| Strand | Forward strand | ||
| Band | |||
| Transcripts |
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| Interactions | |||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Orthologs | |||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||
| NETPATH | |||
| REACTOME |
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Signal Transduction pathway
regulation of FZD by ubiquitination pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
Disease pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
regulation of FZD by ubiquitination pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
TCF dependent signaling in response to WNT pathway
Signal Transduction pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
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| KEGG | |||
| INOH | |||
| PID NCI | |||
| Cross-References | |||
| SwissProt | |||
| TrEMBL | F1MH47 | ||
| UniProt Splice Variant | |||
| Entrez Gene | 517783 | ||
| UniGene | |||
| RefSeq | XM_002692278 XM_595960 | ||
| HUGO | HGNC:16175 | ||
| OMIM | |||
| CCDS | |||
| HPRD | |||
| IMGT | |||
| EMBL | DAAA02036371 | ||
| GenPept | |||
| RNA Seq Atlas | 517783 | ||