Bos taurus Gene: BT.64603
Summary
InnateDB Gene IDBG-641456.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.64603
Gene Name casein kinase II subunit alpha
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012341
Encoded Proteins
casein kinase II subunit alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Feb 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:61082324-61106498
Strand Forward strand
Band
Transcripts
ENSBTAT00000057062 ENSBTAP00000050939
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 325 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 325 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
TNFalpha pathway
Leptin pathway
REACTOME
Developmental Biology pathway
WNT mediated activation of DVL pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Axon guidance pathway
Signal Transduction pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
Condensation of Prometaphase Chromosomes pathway
M Phase pathway
TCF dependent signaling in response to WNT pathway
L1CAM interactions pathway
Signal transduction by L1 pathway
Cell Cycle, Mitotic pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
Cell Cycle, Mitotic pathway
Disease pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
Cell Cycle pathway
M Phase pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
TCF dependent signaling in response to WNT pathway
Mitotic Prometaphase pathway
Axon guidance pathway
Signal transduction by L1 pathway
Condensation of Prometaphase Chromosomes pathway
L1CAM interactions pathway
Developmental Biology pathway
Signal Transduction pathway
WNT mediated activation of DVL pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
KEGG
Wnt signaling pathway pathway
Adherens junction pathway
Tight junction pathway
Wnt signaling pathway pathway
Adherens junction pathway
Tight junction pathway
INOH
PID BIOCARTA
Segmentation clock [Biocarta view]
Lissencephaly gene (lis1) in neuronal migration and development [Biocarta view]
Inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages [Biocarta view]
Bcr signaling pathway [Biocarta view]
Pdgf signaling pathway [Biocarta view]
Nerve growth factor pathway (ngf) [Biocarta view]
Calcium signaling by hbx of hepatitis b virus [Biocarta view]
Tpo signaling pathway [Biocarta view]
Multi-step regulation of transcription by pitx2 [Biocarta view]
Igf-1 signaling pathway [Biocarta view]
Wnt signaling pathway [Biocarta view]
PID NCI
Alpha-synuclein signaling
Presenilin action in Notch and Wnt signaling
BCR signaling pathway
Role of Calcineurin-dependent NFAT signaling in lymphocytes
Lissencephaly gene (LIS1) in neuronal migration and development
PDGFR-alpha signaling pathway
Cross-References
SwissProt
TrEMBL E1BH82
UniProt Splice Variant
Entrez Gene 282419
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036375 DAAA02036376
GenPept
RNA Seq Atlas 282419
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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