|Bos taurus Gene: ASIP|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||Agouti-signaling protein|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101440:
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 13:64234645-64239783|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|Pathway Predictions based on Human Orthology Data|
Insulin-mediated glucose transport
|UniProt Splice Variant|
|RNA Seq Atlas|
|Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas
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