|Bos taurus Gene: MYO9B|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099331:
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
|Genomic Location||Chromosome 7:5804898-5913540|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by Rho GTPases pathway
Innate Immune System pathway
Signal Transduction pathway
Immune System pathway
Rho GTPase cycle pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Regulation of RhoA activity
|UniProt Splice Variant|
|EMBL||DAAA02019082 DAAA02019083 DAAA02019084|
|RNA Seq Atlas||513493|
|Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas
(Move your mouse over the image to view a more detailed version)