Version 5.4
Bos taurus Gene: SCLY
Summary
InnateDB Gene IDBG-642202.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCLY
Gene Name Selenocysteine lyase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017826
Encoded Proteins
IDBP-694637
Selenocysteine lyase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132330:
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:118043316-118073266
Strand Forward strand
Band
Transcripts
ENSBTAT00000013719 ENSBTAP00000013719
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0009000 selenocysteine lyase activity
GO:0016740 transferase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0001887 selenium compound metabolic process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
GO:0032868 response to insulin
GO:1900408 negative regulation of cellular response to oxidative stress
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000132330
View Gene Order
ENSMUSG00000026307
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00450
Selenocompound metabolism pathway
mmu00450
Selenocompound metabolism pathway
INOH
PID NCI
Cross-References
SwissProt A2VDS1
TrEMBL
UniProt Splice Variant
Entrez Gene 790815
UniGene Bt.9081
RefSeq NM_001083804 XM_005205028
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133375
GenPept AAI33376
RNA Seq Atlas 790815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca