Version 5.4
Bos taurus Gene: BPI
Summary
InnateDB Gene IDBG-642592.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BPI
Gene Name Bactericidal permeability-increasing protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014046
Encoded Proteins
IDBP-695060
Bactericidal permeability-increasing protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:67835164-67861379
Strand Forward strand
Band
Transcripts
ENSBTAT00000018669 ENSBTAP00000018669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001530 lipopolysaccharide binding
GO:0008289 lipid binding
Biological Process
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043031 negative regulation of macrophage activation
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P17453
TrEMBL F1MQ17
UniProt Splice Variant
Entrez Gene 280734
UniGene Bt.103
RefSeq NM_173895
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102310 DAAA02036561 DAAA02036562 X52563
GenPept AAI02311 CAA36797
RNA Seq Atlas 280734

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca