InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.64156

Summary

InnateDB Gene

IDBG-642645.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.64156

Gene Name

glutaminase kidney isoform, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007863

Encoded Proteins

IDBP-695125

glutaminase kidney isoform, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115419:
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:79798261-79852401

Strand

Forward strand

Band

Transcripts

ENSBTAT00000010348

ENSBTAP00000010348

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004359	glutaminase activity
GO:0005515	protein binding

Biological Process

GO:0001967	suckling behavior
GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0006537	glutamate biosynthetic process
GO:0006541	glutamine metabolic process
GO:0006543	glutamine catabolic process
GO:0007268	synaptic transmission
GO:0051289	protein homotetramerization