Bos taurus Gene: SRPR
Summary
InnateDB Gene IDBG-642747.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRPR
Gene Name Signal recognition particle receptor subunit alpha
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014105
Encoded Proteins
Signal recognition particle receptor subunit alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182934:
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:29986076-29991236
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018762 ENSBTAP00000018762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005047 signal recognition particle binding
GO:0005525 GTP binding
GO:0017111 nucleoside-triphosphatase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006810 transport
GO:0006886 intracellular protein transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005785 signal recognition particle receptor complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
SRP-dependent cotranslational protein targeting to membrane pathway
Gene Expression pathway
Translation pathway
IRE1alpha activates chaperones pathway
Metabolism of proteins pathway
XBP1(S) activates chaperone genes pathway
Unfolded Protein Response (UPR) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
XBP1(S) activates chaperone genes pathway
IRE1alpha activates chaperones pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Unfolded Protein Response (UPR) pathway
Translation pathway
Metabolism of proteins pathway
Gene Expression pathway
Unfolded Protein Response (UPR) pathway
Translation pathway
Metabolism of proteins pathway
IRE1alpha activates chaperones pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Gene Expression pathway
XBP1(S) activates chaperone genes pathway
KEGG
Protein export pathway
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt Q3MHE8
TrEMBL F1MNJ2
UniProt Splice Variant
Entrez Gene 281504
UniGene Bt.5518
RefSeq NM_001075122
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105264 DAAA02063109
GenPept AAI05265
RNA Seq Atlas 281504