Version 5.4
Bos taurus Gene: BT.102104
Summary
InnateDB Gene IDBG-643273.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.102104
Gene Name rho GTPase-activating protein 24
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003959
Encoded Proteins
IDBP-695820
rho GTPase-activating protein 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138639:
ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:102500170-102666713
Strand Forward strand
Band
Transcripts
ENSBTAT00000005165 ENSBTAP00000005165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0030675 Rac GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0032863 activation of Rac GTPase activity
GO:0035021 negative regulation of Rac protein signal transduction
GO:0035313 wound healing, spreading of epidermal cells
GO:1900028 negative regulation of ruffle assembly
Cellular Component
GO:0005622 intracellular
GO:0005925 focal adhesion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000138639
View Gene Order
ENSMUSG00000057315
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MHI2
UniProt Splice Variant
Entrez Gene 539902
UniGene Bt.102104
RefSeq NM_001102234 XM_005208198 XM_005208199 XM_005208201 XM_005208202 XM_005208203
HUGO HGNC:25361
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02018327 DAAA02018328
GenPept
RNA Seq Atlas 539902

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca