Bos taurus Gene: BT.56359
Summary
InnateDB Gene IDBG-643746.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.56359
Gene Name desmoglein-3 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000039483
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134757:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 24:25978319-26009716
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002538 ENSBTAP00000002538
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Apoptotic cleavage of cell adhesion proteins pathway
Apoptotic cleavage of cellular proteins pathway
Apoptotic execution phase pathway
Apoptosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BM91
UniProt Splice Variant
Entrez Gene 529902
UniGene Bt.13758
RefSeq NM_001192685
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02056457
GenPept
RNA Seq Atlas 529902
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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