Version 5.4
Bos taurus Gene: TM7SF2
Summary
InnateDB Gene IDBG-644134.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TM7SF2
Gene Name delta(14)-sterol reductase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005069
Encoded Proteins
IDBP-696749
delta(14)-sterol reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149809:
Gene Information
Type Protein coding
Genomic Location Chromosome 29:43981731-43986407
Strand Forward strand
Band
Transcripts
ENSBTAT00000006683 ENSBTAP00000006683
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000149809
View Gene Order
ENSMUSG00000024799
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_147904
Activation of gene expression by SREBF (SREBP) pathway
REACT_147797
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_9405
Cholesterol biosynthesis pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_198969
Activation of gene expression by SREBF (SREBP) pathway
REACT_198968
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_208531
Cholesterol biosynthesis pathway
KEGG
hsa00100
Steroid biosynthesis pathway
mmu00100
Steroid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q17QS8
UniProt Splice Variant
Entrez Gene 282384
UniGene Bt.106671
RefSeq NM_174622
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118202 DAAA02063550
GenPept AAI18203
RNA Seq Atlas 282384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca