Version 5.4
Bos taurus Gene: IMPAD1
Summary
InnateDB Gene IDBG-644473.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMPAD1
Gene Name Inositol monophosphatase 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015637
Encoded Proteins
IDBP-697113
Inositol monophosphatase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104331:
This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:25544907-25560879
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020766 ENSBTAP00000020766
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008254 3'-nucleotidase activity
GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0001501 skeletal system development
GO:0001958 endochondral ossification
GO:0002063 chondrocyte development
GO:0006021 inositol biosynthetic process
GO:0009791 post-embryonic development
GO:0016311 dephosphorylation
GO:0030204 chondroitin sulfate metabolic process
GO:0042733 embryonic digit morphogenesis
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104331
View Gene Order
ENSMUSG00000066324
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
hsa00920
Sulfur metabolism pathway
mmu00920
Sulfur metabolism pathway
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q2KJ53
TrEMBL
UniProt Splice Variant
Entrez Gene 532797
UniGene Bt.12649
RefSeq NM_001046335
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105514
GenPept AAI05515
RNA Seq Atlas 532797

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca