Version 5.4
Bos taurus Protein: IMPAD1
Summary
InnateDB Protein IDBP-697113.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMPAD1
Protein Name Inositol monophosphatase 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020766
InnateDB Gene IDBG-644473 (IMPAD1)
Protein Structure
UniProt Annotation
Function May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. {ECO:0000250}.
Subcellular Localization Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008254 3'-nucleotidase activity
GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
GO:0052834 inositol monophosphate phosphatase activity
Biological Process
GO:0001501 skeletal system development
GO:0001958 endochondral ossification
GO:0002063 chondrocyte development
GO:0006021 inositol biosynthetic process
GO:0009791 post-embryonic development
GO:0016311 dephosphorylation
GO:0030204 chondroitin sulfate metabolic process
GO:0042733 embryonic digit morphogenesis
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000760 Inositol monophosphatase
PFAM PF00459
PRINTS PR00377
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KJ53
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 532797
UniGene Bt.12649
RefSeq NP_001039800
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105514
GenPept AAI05515

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca