Version 5.4
Bos taurus Gene: TBC1D10C
Summary
InnateDB Gene IDBG-644700.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D10C
Gene Name carabin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013133
Encoded Proteins
IDBP-697357
TBC1 domain family, member 10C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175463:
The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:45942347-45947879
Strand Forward strand
Band
Transcripts
ENSBTAT00000017459 ENSBTAP00000017459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000175463
View Gene Order
ENSMUSG00000040247
View Gene Order
Cross-References
SwissProt
TrEMBL A6QQB2
UniProt Splice Variant
Entrez Gene 520599
UniGene Bt.18238
RefSeq NM_001102060
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149744 DAAA02063619
GenPept AAI49745
RNA Seq Atlas 520599

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca