Homo sapiens Gene: TBC1D10C
Summary
InnateDB Gene IDBG-60280.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D10C
Gene Name TBC1 domain family, member 10C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000175463
Encoded Proteins
TBC1 domain family, member 10C
TBC1 domain family, member 10C
TBC1 domain family, member 10C
TBC1 domain family, member 10C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:67403915-67410089
Strand Forward strand
Band q13.2
Transcripts
ENST00000312390 ENSP00000310193
ENST00000526387 ENSP00000435543
ENST00000530967
ENST00000529635 ENSP00000435829
ENST00000542590 ENSP00000443654
ENST00000533745
ENST00000529132
ENST00000526474
ENST00000524662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001256508 NM_198517 XM_006718538 XM_006718539 XM_006718540 XM_006718541 XM_006718542 XM_006718543 XM_006718544 XM_006718545
HUGO
OMIM
CCDS CCDS58150 CCDS8162
HPRD 13330
IMGT
EMBL
GenPept
RNA Seq Atlas