Version 5.4
Bos taurus Gene: AIP
Summary
InnateDB Gene IDBG-644744.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AIP
Gene Name AH receptor-interacting protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010478
Encoded Proteins
IDBP-697412
AH receptor-interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 25911105
[Homo sapiens] AIP is a novel inhibitor of IRF7 and a negative regulator of innate antiviral signalling.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110711:
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:46012079-46018138
Strand Forward strand
Band
Transcripts
ENSBTAT00000013841 ENSBTAP00000013841
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0005515 protein binding
GO:0036004 GAF domain binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0006626 protein targeting to mitochondrion
GO:0006805 xenobiotic metabolic process
GO:0022417 protein maturation by protein folding
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000110711
View Gene Order
ENSMUSG00000024847
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3SZ99
UniProt Splice Variant
Entrez Gene 360190
UniGene Bt.49084
RefSeq NM_183082
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103018 DAAA02063623 DAAA02063624
GenPept AAI03019
RNA Seq Atlas 360190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca