Version 5.4
| Bos taurus Gene: PTPRU | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-644839.3 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | PTPRU | ||||||||||||||||
| Gene Name | receptor-type tyrosine-protein phosphatase U precursor | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Bos taurus | ||||||||||||||||
| Ensembl Gene | ENSBTAG00000012848 | ||||||||||||||||
| Encoded Proteins |
protein tyrosine phosphatase, receptor type, U
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000060656:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 2:124819576-124906896 | ||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||
| Band | |||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH |
KitReceptor pathway
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| REACTOME |
Signaling by SCF-KIT pathway
Signal Transduction pathway
Signaling by SCF-KIT pathway
Signal Transduction pathway
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| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | F1MD22 | ||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | 535675 | ||||||||||||||||
| UniGene | Bt.12699 | ||||||||||||||||
| RefSeq | NM_001191494 XM_005203215 XM_005203216 | ||||||||||||||||
| HUGO | HGNC:9683 | ||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | |||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| EMBL | DAAA02006319 DAAA02006320 | ||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | 535675 | ||||||||||||||||