InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PTPRU

Summary

InnateDB Protein

IDBP-697507.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPRU

Protein Name

protein tyrosine phosphatase, receptor type, U

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017076

InnateDB Gene

IDBG-644839 (PTPRU)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0016311	dephosphorylation
GO:0016337	single organismal cell-cell adhesion
GO:0030336	negative regulation of cell migration
GO:0034109	homotypic cell-cell adhesion
GO:0034394	protein localization to cell surface
GO:0060070	canonical Wnt signaling pathway

Cellular Component

GO:0005911	cell-cell junction
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR000998 MAM domain
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00629
PF00041
PF01108

PRINTS

PR00700
PR00020

PIRSF

SMART

SM00194
SM00137
SM00404
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt