InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CHL1

Summary

InnateDB Gene

IDBG-644887.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHL1

Gene Name

neural cell adhesion molecule L1-like protein precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002471

Encoded Proteins

IDBP-697580

cell adhesion molecule with homology to L1CAM (close homolog of L1)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134121:
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Nov 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:26101271-26322519

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000032069

ENSBTAP00000032011

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0005515	protein binding

Biological Process

GO:0001764	neuron migration
GO:0007411	axon guidance
GO:0008344	adult locomotory behavior
GO:0031175	neuron projection development
GO:0035640	exploration behavior
GO:0043524	negative regulation of neuron apoptotic process
GO:0050890	cognition