Version 5.4
Mus musculus Gene: Chl1
Summary
InnateDB Gene IDBG-173444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chl1
Gene Name cell adhesion molecule with homology to L1CAM
Synonyms A530023M13Rik; AI465420; CALL; LICAM2
Species Mus musculus
Ensembl Gene ENSMUSG00000030077
Encoded Proteins
IDBP-173448
cell adhesion molecule with homology to L1CAM
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134121:
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:103510876-103733035
Strand Forward strand
Band E1
Transcripts
ENSMUST00000066905 ENSMUSP00000063933
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0005515 protein binding
Biological Process
GO:0001764 neuron migration
GO:0007411 axon guidance
GO:0008344 adult locomotory behavior
GO:0031103 axon regeneration
GO:0031175 neuron projection development
GO:0035640 exploration behavior
GO:0043524 negative regulation of neuron apoptotic process
GO:0050890 cognition
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0045177 apical part of cell
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134121
View Gene Order
ENSBTAG00000002471
Not yet available
Pathways
NETPATH
REACTOME
REACT_198267
CHL1 interactions pathway
REACT_261444
Axon guidance pathway
REACT_219680
L1CAM interactions pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22292
CHL1 interactions pathway
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.251288
RefSeq NM_007697 XM_006505472
OMIM
CCDS CCDS39582
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca