Version 5.4
Bos taurus Gene: UNC5A
Summary
InnateDB Gene IDBG-645123.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UNC5A
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014897
Encoded Proteins
IDBP-697806
unc-5 homolog A (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113763:
UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:39677304-39692612
Strand Forward strand
Band
Transcripts
ENSBTAT00000043831 ENSBTAP00000041373
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0033564 anterior/posterior axon guidance
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000113763
View Gene Order
ENSMUSG00000025876
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22128
Role of DCC in regulating apoptosis pathway
REACT_22384
Netrin mediated repulsion signals pathway
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_578
Apoptosis pathway
REACT_13648
Regulation of Apoptosis pathway
REACT_258521
Apoptosis pathway
REACT_229826
Netrin-1 signaling pathway
REACT_252543
Role of DCC in regulating apoptosis pathway
REACT_227606
Regulation of Apoptosis pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_253341
Netrin mediated repulsion signals pathway
KEGG
hsa04360
Axon guidance pathway
mmu04360
Axon guidance pathway
INOH
PID NCI
netrin_pathway
Netrin-mediated signaling events
Cross-References
SwissProt
TrEMBL F1MQ73
UniProt Splice Variant
Entrez Gene 506037
UniGene Bt.109918 Bt.25382
RefSeq XM_005199023 XM_005209161
HUGO HGNC:12567
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020044
GenPept
RNA Seq Atlas 506037

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca