|Bos taurus Gene: TRIM63|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||E3 ubiquitin-protein ligase TRIM63|
E3 ubiquitin-protein ligase TRIM63
|Useful resources||Stemformatics EHFPI ImmGen|
|InnateDB Annotation from Orthologs|
[Homo sapiens] TRIM63 was identified in a systematic screen for positive regulators of innate immune responses.
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158022:
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
|Genomic Location||Chromosome 2:127615050-127630608|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 82 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
|UniProt Splice Variant|
|EMBL||BC112721 DAAA02006379 DAAA02006380|
|RNA Seq Atlas||528912|