Version 5.4
Bos taurus Gene: HNRNPAB
Summary
InnateDB Gene IDBG-645319.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNRNPAB
Gene Name heterogeneous nuclear ribonucleoprotein A/B
Synonyms HNRPAB
Species Bos taurus
Ensembl Gene ENSBTAG00000013627
Encoded Proteins
IDBP-698024
heterogeneous nuclear ribonucleoprotein A/B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197451:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:40638057-40643916
Strand Forward strand
Band
Transcripts
ENSBTAT00000018114 ENSBTAP00000018114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0019013 viral nucleocapsid
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000197451
View Gene Order
ENSMUSG00000020358
View Gene Order
Cross-References
SwissProt
TrEMBL Q3ZC44
UniProt Splice Variant
Entrez Gene 513410
UniGene Bt.58979 Bt.81910
RefSeq NM_001040522
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102923 DAAA02020062 DAAA02020063
GenPept AAI02924
RNA Seq Atlas 513410

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca