Bos taurus Gene: HNRNPR
Summary
InnateDB Gene IDBG-645473.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNRNPR
Gene Name heterogeneous nuclear ribonucleoprotein R
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016578
Encoded Proteins
heterogeneous nuclear ribonucleoprotein R
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125944:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:130103590-130132649
Strand Forward strand
Band
Transcripts
ENSBTAT00000022054 ENSBTAP00000022054
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 117 interaction(s) predicted by orthology.
Predicted by orthology
Total 117 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0030529 ribonucleoprotein complex
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL A3KMV6
UniProt Splice Variant
Entrez Gene 512479
UniGene Bt.3687
RefSeq NM_001082608 XM_005203111 XM_005203112 XM_005203113 XM_005203114 XM_005203115 XM_005203116 XM_005203117
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133299 DAAA02006438
GenPept AAI33300
RNA Seq Atlas 512479
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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