Version 5.4
Bos taurus Gene: MUC5B
Summary
InnateDB Gene IDBG-645630.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUC5B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008274
Encoded Proteins
IDBP-698373
mucin 5B, oligomeric mucus/gel-forming
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117983:
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:51371105-51461957
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010897 ENSBTAP00000010897
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030414 peptidase inhibitor activity
Biological Process
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000117983
View Gene Order
ENSMUSG00000066108
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115835
Termination of O-glycan biosynthesis pathway
REACT_115606
O-linked glycosylation of mucins pathway
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa04970
Salivary secretion pathway
mmu04970
Salivary secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G5E5A7
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:7516
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02063796 DAAA02063797 DAAA02063798 DAAA02063799 DAAA02063800
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca