Version 5.4
| Bos taurus Gene: SEMA6D | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-646685.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SEMA6D | ||||||||
| Gene Name | semaphorin-6D precursor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000016800 | ||||||||
| Encoded Proteins |
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137872:
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:62863669-62920660 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Other semaphorin interactions pathway
Developmental Biology pathway
Semaphorin interactions pathway
Axon guidance pathway
Axon guidance pathway
Developmental Biology pathway
Semaphorin interactions pathway
Other semaphorin interactions pathway
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| KEGG |
Axon guidance pathway
Axon guidance pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BNY3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 518458 | ||||||||
| UniGene | Bt.106023 Bt.19862 | ||||||||
| RefSeq | NM_001191133 | ||||||||
| HUGO | HGNC:16770 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02029127 DAAA02029128 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 518458 | ||||||||