InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SOCS4

Summary

InnateDB Gene

IDBG-646714.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SOCS4

Gene Name

Suppressor of cytokine signaling 4

Synonyms

SOCS6

Species

Bos taurus

Ensembl Gene

ENSBTAG00000021988

Encoded Proteins

IDBP-699543

Suppressor of cytokine signaling 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000180008:
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:67735433-67749358

Strand

Forward strand

Band

Transcripts

ENSBTAT00000029320

ENSBTAP00000029320

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
GO:0009968	negative regulation of signal transduction
GO:0016567	protein ubiquitination
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556	intracellular signal transduction
GO:0040008	regulation of growth