Homo sapiens Gene: INTS4
Summary
InnateDB Gene IDBG-65759.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS4
Gene Name integrator complex subunit 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000149262
Encoded Proteins
integrator complex subunit 4
integrator complex subunit 4
integrator complex subunit 4
integrator complex subunit 4
integrator complex subunit 4
integrator complex subunit 4
integrator complex subunit 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:77878720-77994678
Strand Reverse strand
Band q14.1
Transcripts
ENST00000433818 ENSP00000407787
ENST00000534064 ENSP00000434466
ENST00000533180
ENST00000531059
ENST00000525268
ENST00000525931
ENST00000529807 ENSP00000433644
ENST00000534408 ENSP00000432776
ENST00000524766 ENSP00000436248
ENST00000527522 ENSP00000435758
ENST00000535943 ENSP00000441084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q96HW7
TrEMBL
UniProt Splice Variant
Entrez Gene 92105
UniGene Hs.533723 Hs.601988
RefSeq NM_033547 XM_005274393
HUGO HGNC:25048
OMIM 611348
CCDS CCDS31644
HPRD 12386
IMGT
EMBL AF172822 BC006369 BC008013 BC009859 BC009995 BC015664 BK005723
GenPept AAH06369 AAH08013 AAH09859 AAH09995 AAH15664 AAQ13616 DAA05723
RNA Seq Atlas 92105