Version 5.4
Homo sapiens Gene: INTS4
Summary
InnateDB Gene IDBG-65759.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS4
Gene Name integrator complex subunit 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000149262
Encoded Proteins
IDBP-381525
integrator complex subunit 4
IDBP-583448
integrator complex subunit 4
IDBP-592549
integrator complex subunit 4
IDBP-583612
integrator complex subunit 4
IDBP-594080
integrator complex subunit 4
IDBP-593863
integrator complex subunit 4
IDBP-592055
integrator complex subunit 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:77878720-77994678
Strand Reverse strand
Band q14.1
Transcripts
ENST00000433818 ENSP00000407787
ENST00000534064 ENSP00000434466
ENST00000533180
ENST00000531059
ENST00000525268
ENST00000525931
ENST00000529807 ENSP00000433644
ENST00000534408 ENSP00000432776
ENST00000524766 ENSP00000436248
ENST00000527522 ENSP00000435758
ENST00000535943 ENSP00000441084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025133
View Gene Order
ENSBTAG00000010505
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.533723 Hs.601988
RefSeq NM_033547 XM_005274393
HUGO
OMIM
CCDS CCDS31644
HPRD 12386
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca