Homo sapiens Gene: LIM2
InnateDB Gene IDBG-65871.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIM2
Gene Name lens intrinsic membrane protein 2, 19kDa
Synonyms CTRCT19; MP17; MP19
Species Homo sapiens
Ensembl Gene ENSG00000105370
Encoded Proteins
lens intrinsic membrane protein 2, 19kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:51379909-51387960
Strand Reverse strand
Band q13.41
ENST00000221973 ENSP00000221973
ENST00000596399 ENSP00000472090
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005212 structural constituent of eye lens
Biological Process
GO:0002088 lens development in camera-type eye
GO:0007043 cell-cell junction assembly
GO:0043010 camera-type eye development
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0031982 vesicle
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt P55344
UniProt Splice Variant
Entrez Gene 3982
UniGene Hs.162754
RefSeq NM_030657 NM_001161748
OMIM 154045
CCDS CCDS12831 CCDS59415
HPRD 01097
EMBL AF305941 AF340019 AF340020 BC069430 BC074916 BC074917 BC126139 CH471135 L04193
GenPept AAG32328 AAH69430 AAH74916 AAH74917 AAI26140 AAK26327 AAK26328 EAW72010
RNA Seq Atlas 3982