Version 5.4
Homo sapiens Gene: PRPF31
Summary
InnateDB Gene IDBG-68110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPF31
Gene Name PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105618
Encoded Proteins
IDBP-68112
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
IDBP-247053
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
IDBP-384533
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
IDBP-384538
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
IDBP-384539
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
IDBP-384540
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:54115410-54131719
Strand Forward strand
Band q13.42
Transcripts
ENST00000321030 ENSP00000324122
ENST00000391755 ENSP00000375635
ENST00000445811 ENSP00000395894
ENST00000419967 ENSP00000405166
ENST00000445124 ENSP00000408980
ENST00000447810 ENSP00000395089
ENST00000467851
ENST00000466404
ENST00000498612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 62 [view]
Protein-Protein 61 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0044822 poly(A) RNA binding
GO:0070990 snRNP binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005684 U2-type spliceosomal complex
GO:0005687 U4 snRNP
GO:0005690 U4atac snRNP
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071339 MLL1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008373
View Gene Order
ENSBTAG00000007757
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_015629 XM_006723137
HUGO
OMIM
CCDS CCDS12879
HPRD 05917
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca