Homo sapiens Gene: PRPF31
Summary
InnateDB Gene IDBG-68110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRPF31
Gene Name PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105618
Encoded Proteins
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:54115410-54131719
Strand Forward strand
Band q13.42
Transcripts
ENST00000321030 ENSP00000324122
ENST00000391755 ENSP00000375635
ENST00000445811 ENSP00000395894
ENST00000419967 ENSP00000405166
ENST00000445124 ENSP00000408980
ENST00000447810 ENSP00000395089
ENST00000467851
ENST00000466404
ENST00000498612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 62 [view]
Protein-Protein 61 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0044822 poly(A) RNA binding
GO:0070990 snRNP binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005684 U2-type spliceosomal complex
GO:0005687 U4 snRNP
GO:0005690 U4atac snRNP
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071339 MLL1 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL E7EN72 E7ESX0 E7EU94 E7EVX8
UniProt Splice Variant
Entrez Gene 26121
UniGene
RefSeq NM_015629 XM_006723137
HUGO HGNC:15446
OMIM 606419
CCDS CCDS12879
HPRD 05917
IMGT
EMBL AC012314
GenPept
RNA Seq Atlas 26121