Homo sapiens Gene: NUP85
Summary
InnateDB Gene IDBG-68125.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUP85
Gene Name nucleoporin 85kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125450
Encoded Proteins
nucleoporin 85kDa
nucleoporin 85kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:75205659-75235758
Strand Forward strand
Band q25.1
Transcripts
ENST00000245544 ENSP00000245544
ENST00000449421
ENST00000540768 ENSP00000445855
ENST00000577645
ENST00000582681
ENST00000579838 ENSP00000462364
ENST00000583548
ENST00000583070 ENSP00000463542
ENST00000579298 ENSP00000462749
ENST00000581335
ENST00000583877 ENSP00000463715
ENST00000579324 ENSP00000463382
ENST00000579557 ENSP00000463496
ENST00000581104 ENSP00000461919
ENST00000578830 ENSP00000462920
ENST00000578987 ENSP00000464544
ENST00000580879 ENSP00000463377
ENST00000584155 ENSP00000464433
ENST00000583948
ENST00000579900 ENSP00000463437
ENST00000577561
ENST00000578294
ENST00000583569 ENSP00000462487
ENST00000577208
ENST00000582833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 21 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0005975 carbohydrate metabolic process
GO:0006935 chemotaxis
GO:0007077 mitotic nuclear envelope disassembly
GO:0008645 hexose transport
GO:0010827 regulation of glucose transport
GO:0015031 protein transport
GO:0015758 glucose transport
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0030032 lamellipodium assembly
GO:0044281 small molecule metabolic process
GO:0048246 macrophage chemotaxis
GO:0051028 mRNA transport
GO:0055085 transmembrane transport
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005635 nuclear envelope
GO:0005819 spindle
GO:0005829 cytosol
GO:0016020 membrane
GO:0031080 nuclear pore outer ring
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Vpr-mediated nuclear import of PICs pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Glucose transport pathway
Hexose transport pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Late Phase of HIV Life Cycle pathway
Viral Messenger RNA Synthesis pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Separation of Sister Chromatids pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
Immune System pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Anaphase pathway
Mitotic Prophase pathway
Rev-mediated nuclear export of HIV RNA pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
ISG15 antiviral mechanism pathway
Influenza Life Cycle pathway
Nuclear import of Rev protein pathway
Metabolism pathway
Host Interactions of HIV factors pathway
Resolution of Sister Chromatid Cohesion pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Mitotic Metaphase and Anaphase pathway
Regulatory RNA pathways pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 79902
UniGene Hs.362817
RefSeq NM_024844 XM_005257693 XM_005257692 XM_006722094
HUGO HGNC:8734
OMIM 170285
CCDS CCDS32730
HPRD 01363
IMGT
EMBL
GenPept
RNA Seq Atlas 79902