Homo sapiens Gene: HIST1H1D
Summary
InnateDB Gene IDBG-68753.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIST1H1D
Gene Name histone cluster 1, H1d
Synonyms H1.3; H1D; H1F3; H1s-2;
Species Homo sapiens
Ensembl Gene ENSG00000124575
Encoded Proteins
histone cluster 1, H1d
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:26234268-26234933
Strand Reverse strand
Band p22.2
Transcripts
ENST00000244534 ENSP00000244534
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0031490 chromatin DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006334 nucleosome assembly
GO:0016584 nucleosome positioning
Cellular Component
GO:0000786 nucleosome
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005719 nuclear euchromatin
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Apoptotic execution phase pathway
Cellular responses to stress pathway
Apoptosis induced DNA fragmentation pathway
Formation of Senescence-Associated Heterochromatin Foci (SAHF) pathway
Activation of DNA fragmentation factor pathway
Apoptosis pathway
DNA Damage/Telomere Stress Induced Senescence pathway
Cellular Senescence pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P16402
TrEMBL
UniProt Splice Variant
Entrez Gene 3007
UniGene Hs.136857
RefSeq NM_005320
HUGO HGNC:4717
OMIM 142210
CCDS CCDS4597
HPRD
IMGT
EMBL AF531303 AK312845 AL031777 BC104874 BC111971 CH471087 M60747
GenPept AAA63186 AAI04875 AAI11972 AAN06703 BAG35698 CAB39189 EAW55548
RNA Seq Atlas 3007