Version 5.4
Homo sapiens Gene: PGM5
Summary
InnateDB Gene IDBG-68955.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGM5
Gene Name phosphoglucomutase 5
Synonyms PGMRP;
Species Homo sapiens
Ensembl Gene ENSG00000154330
Encoded Proteins
IDBP-237610
phosphoglucomutase 5
IDBP-237612
phosphoglucomutase 5
IDBP-372183
phosphoglucomutase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:68328308-68531061
Strand Forward strand
Band q21.11
Transcripts
ENST00000396396 ENSP00000379678
ENST00000396392 ENSP00000379674
ENST00000431583 ENSP00000394864
ENST00000472639
ENST00000496758
ENST00000604870
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0016868 intramolecular transferase activity, phosphotransferases
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007155 cell adhesion
Cellular Component
GO:0001725 stress fiber
GO:0005913 cell-cell adherens junction
GO:0005914 spot adherens junction
GO:0005925 focal adhesion
GO:0009898 cytoplasmic side of plasma membrane
GO:0014704 intercalated disc
GO:0016010 dystrophin-associated glycoprotein complex
GO:0030018 Z disc
GO:0030055 cell-substrate junction
GO:0042383 sarcolemma
GO:0043034 costamere
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000041731
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000033190
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.307835
RefSeq NM_021965
HUGO
OMIM
CCDS CCDS6622
HPRD 02990
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca