Version 5.4
Homo sapiens Gene: ZACN
Summary
InnateDB Gene IDBG-69396.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZACN
Gene Name zinc activated ligand-gated ion channel
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186919
Encoded Proteins
IDBP-69398
zinc activated ligand-gated ion channel
IDBP-384667
zinc activated ligand-gated ion channel
IDBP-384672
zinc activated ligand-gated ion channel
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:76071961-76083666
Strand Forward strand
Band q25.1
Transcripts
ENST00000334586 ENSP00000334854
ENST00000425015 ENSP00000397489
ENST00000421794 ENSP00000391936
ENST00000524242
ENST00000591500
ENST00000590045
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
GO:0008270 zinc ion binding
GO:0015276 ligand-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0010043 response to zinc ion
GO:0034220 ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.714919
RefSeq NM_180990
HUGO
OMIM
CCDS CCDS11740
HPRD 17271
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca