Version 5.4
Homo sapiens Gene: LSG1
Summary
InnateDB Gene IDBG-70417.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSG1
Gene Name large subunit GTPase 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000041802
Encoded Proteins
IDBP-70419
large subunit GTPase 1 homolog (S. cerevisiae)
IDBP-386822
large subunit GTPase 1 homolog (S. cerevisiae)
IDBP-386824
large subunit GTPase 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:194640788-194672477
Strand Reverse strand
Band q29
Transcripts
ENST00000265245 ENSP00000265245
ENST00000437613 ENSP00000408264
ENST00000427461 ENSP00000400903
ENST00000475763
ENST00000460584
ENST00000466391
ENST00000461343
ENST00000480853
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0015031 protein transport
GO:0042254 ribosome biogenesis
GO:0051168 nuclear export
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0015030 Cajal body
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022538
View Gene Order
ENSBTAG00000008461
Not yet available
Cross-References
SwissProt Q9H089
TrEMBL F8WFC6
UniProt Splice Variant
Entrez Gene 55341
UniGene Hs.518505 Hs.735549 Hs.738399
RefSeq NM_018385
HUGO HGNC:25652
OMIM 610780
CCDS CCDS33922
HPRD
IMGT
EMBL AC046143 AK002163 AL136897 BC015042 BC040119 BC068500
GenPept AAH15042 AAH40119 AAH68500 BAA92116 CAB66831
RNA Seq Atlas 55341

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca