Version 5.4
Homo sapiens Gene: AFMID
Summary
InnateDB Gene IDBG-70529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AFMID
Gene Name arylformamidase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183077
Encoded Proteins
IDBP-70531
arylformamidase
IDBP-293401
arylformamidase
IDBP-764116
IDBP-762328
IDBP-761010
IDBP-758472
IDBP-758599
IDBP-759600
IDBP-764217
IDBP-764592
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:78187317-78207701
Strand Forward strand
Band q25.3
Transcripts
ENST00000327898 ENSP00000328938
ENST00000409257 ENSP00000386890
ENST00000589664
ENST00000585419
ENST00000591256 ENSP00000466515
ENST00000586542 ENSP00000466566
ENST00000588199 ENSP00000465406
ENST00000588800 ENSP00000464929
ENST00000586731 ENSP00000466241
ENST00000589256 ENSP00000466859
ENST00000589107 ENSP00000467869
ENST00000592988
ENST00000591952 ENSP00000467365
ENST00000591538
ENST00000587750
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004061 arylformamidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006569 tryptophan catabolic process
GO:0008152 metabolic process
GO:0019441 tryptophan catabolic process to kynurenine
GO:0034354 'de novo' NAD biosynthetic process from tryptophan
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017718
View Gene Order
ENSBTAG00000007125
Not yet available
Pathways
NETPATH
REACTOME
REACT_916
Tryptophan catabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00630
Glyoxylate and dicarboxylate metabolism pathway
hsa00380
Tryptophan metabolism pathway
INOH
INOH website
Tryptophan degradation pathway
PID NCI
Cross-References
SwissProt Q63HM1
TrEMBL A5PLM3 K7EIX3 K7EK09 K7ELV9 K7EMI4 K7EMM5 K7EPF8 K7EQK5 W4VSQ7
UniProt Splice Variant
Entrez Gene 125061
UniGene Hs.558614
RefSeq NM_001010982 NM_001145526
HUGO HGNC:20910
OMIM
CCDS CCDS32750 CCDS45801
HPRD
IMGT
EMBL AC087645 BC132824 BC142973 BX648442 CH471099
GenPept AAI32825 AAI42974 CAH56149 EAW89510
RNA Seq Atlas 102723386 102724007 125061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca