|Homo sapiens Gene: LGALS3BP|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||lectin, galactoside-binding, soluble, 3 binding protein|
|Synonyms||90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B;|
lectin, galactoside-binding, soluble, 3 binding protein
|Useful resources||Stemformatics EHFPI ImmGen|
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 17:78971238-78980109|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 85 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas||3959|