Version 5.4
Mus musculus Gene: Lgals3bp
Summary
InnateDB Gene IDBG-214638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lgals3bp
Gene Name lectin, galactoside-binding, soluble, 3 binding protein
Synonyms 90K; CyCAP; MAC-2BP; Ppicap; Tango10b
Species Mus musculus
Ensembl Gene ENSMUSG00000033880
Encoded Proteins
IDBP-214640
lectin, galactoside-binding, soluble, 3 binding protein
IDBP-269077
lectin, galactoside-binding, soluble, 3 binding protein
IDBP-537617
lectin, galactoside-binding, soluble, 3 binding protein
IDBP-534321
lectin, galactoside-binding, soluble, 3 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108679:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:118392751-118402092
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000043722 ENSMUSP00000035579
ENSMUST00000106290 ENSMUSP00000101897
ENSMUST00000144529 ENSMUSP00000120846
ENSMUST00000141459
ENSMUST00000127054 ENSMUSP00000121024
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007155 cell adhesion
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0016020 membrane
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108679
View Gene Order
ENSBTAG00000001368
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3152
RefSeq NM_011150 XM_006532506
OMIM
CCDS CCDS25701
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca