Version 5.4
Homo sapiens Gene: ZNF444
Summary
InnateDB Gene IDBG-71345.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF444
Gene Name zinc finger protein 444
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167685
Encoded Proteins
IDBP-71347
zinc finger protein 444
IDBP-766229
IDBP-762324
IDBP-761716
IDBP-764982
IDBP-762932
IDBP-765299
IDBP-762584
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). This gene is located in a cluster of zinc finger genes on chromosome 19 at q13.4. A pseudogene of this gene is located on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:56132599-56160893
Strand Forward strand
Band q13.43
Transcripts
ENST00000337080 ENSP00000338860
ENST00000587195
ENST00000591564 ENSP00000468762
ENST00000592949 ENSP00000468069
ENST00000587236
ENST00000592171
ENST00000586123 ENSP00000466666
ENST00000587664
ENST00000587467 ENSP00000465171
ENST00000588358 ENSP00000466287
ENST00000593100 ENSP00000465070
ENST00000588203 ENSP00000465466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044876
View Gene Order
ENSBTAG00000046111
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.24545 Hs.613990
RefSeq NM_001253792 NM_018337 XM_005259034 XM_005259035 XM_005259036
HUGO
OMIM
CCDS CCDS12939 CCDS59426
HPRD 08488
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca