Version 5.4
Homo sapiens Protein: ZNF444
Summary
InnateDB Protein IDBP-71347.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF444
Protein Name zinc finger protein 444
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000338860
InnateDB Gene IDBG-71345 (ZNF444)
Protein Structure
UniProt Annotation
Function Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00187}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003309 Transcription regulator SCAN
IPR007087 Zinc finger, C2H2
IPR008916 Retrovirus capsid, C-terminal
IPR015880 Zinc finger, C2H2-like
PFAM PF02023
PF00096
PRINTS
PIRSF
SMART SM00431
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N0Y2
PhosphoSite PhosphoSite-Q8N0Y2
TrEMBL K7ESL2
UniProt Splice Variant
Entrez Gene 55311
UniGene Hs.613990
RefSeq NP_060807
HUGO HGNC:16052
OMIM 607874
CCDS CCDS12939
HPRD 08488
IMGT
EMBL AB052954 AB052955 AC024580 AK001999 AK074063 AL834130 BC021282 CH471135
GenPept AAH21282 BAA92028 BAB84889 BAC02697 BAC02698 CAD38847 EAW72425 EAW72429 EAW72430

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca