Version 5.4
Homo sapiens Gene: TRO
Summary
InnateDB Gene IDBG-71746.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRO
Gene Name trophinin
Synonyms MAGE-d3; MAGED3
Species Homo sapiens
Ensembl Gene ENSG00000067445
Encoded Proteins
IDBP-71748
trophinin
IDBP-71754
trophinin
IDBP-71756
trophinin
IDBP-71760
trophinin
IDBP-229863
trophinin
IDBP-373838
trophinin
IDBP-373848
trophinin
IDBP-373854
trophinin
IDBP-373861
trophinin
IDBP-373864
trophinin
IDBP-373877
trophinin
IDBP-373905
trophinin
IDBP-373906
trophinin
IDBP-373907
trophinin
IDBP-373910
trophinin
IDBP-373911
trophinin
IDBP-373912
trophinin
IDBP-373917
trophinin
IDBP-809952
trophinin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. The encoded protein participates in cell signalling during embryo implantation, and may also be involved in cancer formation. This gene is located near several other closely related genes on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:54920462-54931431
Strand Forward strand
Band p11.21
Transcripts
ENST00000375041 ENSP00000364181
ENST00000375022 ENSP00000364162
ENST00000173898 ENSP00000173898
ENST00000319167 ENSP00000318278
ENST00000399736 ENSP00000382641
ENST00000411534 ENSP00000388947
ENST00000452830 ENSP00000387676
ENST00000430420 ENSP00000411717
ENST00000442098 ENSP00000404645
ENST00000453081 ENSP00000412588
ENST00000445561 ENSP00000404794
ENST00000420798 ENSP00000405126
ENST00000440072 ENSP00000405043
ENST00000431115 ENSP00000407996
ENST00000440759 ENSP00000406574
ENST00000449980 ENSP00000392841
ENST00000416704 ENSP00000404767
ENST00000427099 ENSP00000405311
ENST00000484031
ENST00000474933
ENST00000492142
ENST00000492706
ENST00000475183
ENST00000469211
ENST00000622017 ENSP00000483142
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0007566 embryo implantation
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000025272
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.624969 Hs.633653 Hs.715754 Hs.743294
RefSeq NM_001039705 NM_001271183 NM_001271184 NM_016157 NM_177556 NM_177557 XM_006724599 XM_006724600 XM_006724601 XM_006724602 XM_006724603 XM_006724604 XM_006724605
HUGO
OMIM
CCDS CCDS43958 CCDS43959 CCDS59527 CCDS59528 CCDS59529
HPRD 02134
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca