Version 5.4
Homo sapiens Gene: TMPRSS5
Summary
InnateDB Gene IDBG-71777.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS5
Gene Name transmembrane protease, serine 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166682
Encoded Proteins
IDBP-71779
transmembrane protease, serine 5
IDBP-583453
transmembrane protease, serine 5
IDBP-593734
transmembrane protease, serine 5
IDBP-584022
transmembrane protease, serine 5
IDBP-586031
transmembrane protease, serine 5
IDBP-597116
transmembrane protease, serine 5
IDBP-602740
transmembrane protease, serine 5
IDBP-588227
transmembrane protease, serine 5
IDBP-592778
transmembrane protease, serine 5
IDBP-588270
transmembrane protease, serine 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:113687550-113706373
Strand Reverse strand
Band q23.2
Transcripts
ENST00000299882 ENSP00000299882
ENST00000536856 ENSP00000437937
ENST00000540540 ENSP00000437761
ENST00000545579 ENSP00000441104
ENST00000538955 ENSP00000445528
ENST00000544634 ENSP00000440783
ENST00000544476 ENSP00000445930
ENST00000545265
ENST00000545412
ENST00000539732 ENSP00000443681
ENST00000538770 ENSP00000445502
ENST00000538091 ENSP00000440976
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032268
View Gene Order
ENSBTAG00000017650
Not yet available
Cross-References
SwissProt Q9H3S3
TrEMBL B0YJB1 F5GX83 F5GXT6 F5GYA3 F5H0U3 F5H2M3 G5EA43 G5EA47
UniProt Splice Variant
Entrez Gene 80975
UniGene
RefSeq NM_001288749 NM_001288750 NM_001288751 NM_001288752 NM_030770
HUGO HGNC:14908
OMIM 606751
CCDS CCDS44735 CCDS73390 CCDS73391 CCDS73392 CCDS73393
HPRD
IMGT
EMBL AB028140 AP002436 AP003402 CH471065 EF445039
GenPept ACA06089 BAB20375 EAW67226 EAW67227
RNA Seq Atlas 80975

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca